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Supramolecular systems chemistry

94 RatzkeC.GoreJ

Glutathione is subsequently found at its highest concentrations in tissues at most risk and therefore requiring the most protection from potentially toxic exogenous and endogenous compounds: the liver where the vast majority of detoxification metabolism occurs and, at the cellular level, around organelles which are most exposed and most at risk of potential damage from oxidative stress from reactive oxygen species: mitochondria, peroxisomes and the nuclear matrix (Wu et al., 2004)

Subcutaneous 4T1 tumor-bearing mice model was constructed and then IR780-labled SRB and FeS@SRB were injected intravenously, respectively

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